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Article

BMI1: A Biomarker of Hematologic Malignancies

1 Jan 2016

Abstract excerpt

BMI1 oncogene is a catalytic member of epigenetic repressor polycomb group proteins. It plays a critical role in the regulation of gene expression pattern and consequently several cellular processes during development, including cell cycle progression, senescence, aging, apoptosis, angiogenesis, and importantly self-renewal of adult stem cells of several lineages. Preponderance of evidences indicates that...

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PMID: 27168727
DOI: 10.4137/bic.s33376

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