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Article

Dual functional significance of calcineurin homologous protein 1 binding to Na(+)/H(+) exchanger isoform 1.

American journal of physiology. Cell physiology - 1 Aug 2011

Matsushita Masafumi, Tanaka Hiroo, Mitsui Keiji, Kanazawa Hiroshi

Abstract excerpt

Calcineurin homologous protein 1 (CHP1) binds to the hydrophilic tail of the Na(+)/H(+) exchanger isoform 1 (NHE1). Previous gene knockout of CHP1 revealed that the loss of CHP1 caused a decrease in the total amount of NHE1, suggesting the destabilization of NHE1 molecules without CHP1 (Matsushita et al., Am J Physiol Cell Physiol 293: C246-C254, 2007). However, Pang et al. (J Biol Chem 276: 17367-17372, 2001)...

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Share to Calcium-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21543739
DOI: 10.1152/ajpcell.00404.2010

Genes

CHP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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