Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of calcineurin homologous protein-1 in chicken B lymphoma DT40 cells destabilizes Na+/H+ exchanger isoform-1 protein.

American journal of physiology. Cell physiology - 1 Jul 2007

Matsushita Masafumi, Sano Yoshie, Yokoyama Shunsuke, Takai Tomoyo, Inoue Hiroki, Mitsui Keiji, Todo Kagefumi, Ohmori Hitoshi, Kanazawa Hiroshi

Abstract excerpt

NHE1/SLC9A1 is a ubiquitous isoform of vertebrate Na(+)/H(+) exchangers (NHEs) functioning in maintaining intracellular concentrations of Na(+) and H(+) ions. Calcineurin homologous protein-1 (CHP1) binds to the hydrophilic region of NHE1 and regulates NHE1 activity but reportedly does not play a role in translocating NHE1 from the endoplasmic reticulum to the plasma membrane. However, an antiport function of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amiloride
Share to Calcium-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cation Transport Proteins

Share to Lymphoma, B-Cell

Share to Myristic Acid

Share to Opossums

Share to Sodium

Share to Sodium-Hydrogen Exchangers

Source

Identifiers

PMID: 17392381
DOI: 10.1152/ajpcell.00464.2006

Genes

CHP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of calcineurin homologous protein-1 in chicken B lymphoma DT40 cells destabilizes Na+/H+ exchanger isoform-1 protein.PMID 17392381Read ↗

Dual functional significance of calcineurin homologous protein 1 binding to Na(+)/H(+) exchanger isoform 1.Semantic proximity Read ↗

Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers.Semantic proximity Read ↗

Role of calcineurin B homologous protein in pH regulation by the Na+/H+ exchanger 1: tightly bound Ca2+ ions as important structural elements.Semantic proximity Read ↗

Calcineurin homologous proteins regulate the membrane localization and activity of sodium/proton exchangers in C. elegans.Semantic proximity Read ↗

Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish.Semantic proximity Read ↗

Anion exchanger 1b, but not sodium-bicarbonate cotransporter 1b, plays a role in transport functions of zebrafish H+-ATPase-rich cells.Semantic proximity Read ↗

Characterization of the Na+/H+ exchanger in human choriocarcinoma (BeWo) cells.Semantic proximity Read ↗

Variant chicken AE1 anion exchangers possess divergent NH(2)-terminal cytoplasmic domains.Semantic proximity Read ↗

Expression and characterization of the Na+/H+ exchanger in the mammalian myocardium.Semantic proximity Read ↗

Intracellular trafficking of variant chicken kidney AE1 anion exchangers: role Of alternative NH(2) termini in polarized sorting and Golgi recycling.Semantic proximity Read ↗

Endothelin-1 enhances the activity of Na+/Ca2+ exchanger type 1 in renal epithelial cells.Semantic proximity Read ↗

Separate C-terminal domains of the epithelial specific brush border Na+/H+ exchanger isoform NHE3 are involved in stimulation and inhibition by protein kinases/growth factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.