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Article

Prognostic impact of FLT3-ITD load in NPM1 mutated acute myeloid leukemia.

Leukemia - 1 Aug 2011

Schnittger S, Bacher U, Kern W, Alpermann T, Haferlach C, Haferlach T

Abstract excerpt

High FLT3-ITD/wildtype (wt) load in FLT3-ITD-mutated AML has been associated with adverse impact on outcome in several studies. To clarify whether FLT3-ITD load as expressed as FLT3-ITD/wt ratio is also relevant in patients with NPM1 mutated AML, we assessed the FLT3-ITD mutation status and FLT3-ITD/wt ratio by fragment analysis in 638 NPM1mut AML (339 females; 299 males; 17.8-88.0 years), and analyzed its...

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Source

Identifiers

PMID: 21537333
DOI: 10.1038/leu.2011.97

Genes

FLT3
EFS
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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