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Article

Activity-dependent mRNA splicing controls ER export and synaptic delivery of NMDA receptors.

Neuron - 30 Oct 2003

Mu Yuanyue, Otsuka Takeshi, Horton April C, Scott Derek B, Ehlers Michael D

Abstract excerpt

Activity-dependent targeting of NMDA receptors (NMDARs) is a key feature of synapse formation and plasticity. Although mechanisms for rapid trafficking of glutamate receptors have been identified, the molecular events underlying chronic accumulation or loss of synaptic NMDARs have remained unclear. Here we demonstrate that activity controls NMDAR synaptic accumulation by regulating forward trafficking at the...

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Source

Identifiers

PMID: 14642281
DOI: 10.1016/s0896-6273(03)00676-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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