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Article

Drosophila sbo regulates lifespan through its function in the synthesis of coenzyme Q in vivo.

Journal of genetics and genomics = Yi chuan xue bao - 20 Jun 2011

Liu Jiyong, Wu Qinghua, He Dianlu, Ma Tengyu, Du Li, Dui Wen, Guo Xiaoyan, Jiao Renjie

Abstract excerpt

CoQ is an essential electron carrier in the mitochondrial respiratory chain of both eukaryotes and prokaryotes. It consists of a benzoquinone head group and a hydrophobic polyisoprenoid tail. The genes (COQ1-9) involved in CoQ biosynthesis have been characterized in yeast. In this study, we generated and molecularly characterized a mutant allele of a novel Drosophila gene, sbo, which encodes a protein that is...

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Identifiers

PMID: 21703546
DOI: 10.1016/j.jgg.2011.05.002

Genes

COQ2

Provenance

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