Article
The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis.
The Journal of biological chemistry - 11 Jul 2003
Gin Peter, Hsu Adam Y, Rothman Steven C, Jonassen Tanya, Lee Peter T, Tzagoloff Alexander, Clarke Catherine F
Abstract excerpt
Coenzyme Q (Q) is a lipid that functions as an electron carrier in the mitochondrial respiratory chain in eukaryotes. There are eight complementation groups of Q-deficient Saccharomyces cerevisiae mutants, designated coq1-coq8. Here we have isolated the COQ6 gene by functional complementation and, in contrast to a previous report, find it is not an essential gene. coq6 mutants are unable to grow on nonfermentable...
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