Article
Association of beta-adrenergic receptor polymorphisms and mortality in carvedilol-treated chronic heart-failure patients.
British journal of clinical pharmacology - 1 Apr 2011
Petersen Morten, Andersen Jon T, Hjelvang Brian R, Broedbaek Kasper, Afzal Shoaib, Nyegaard Mette, Børglum Anders D, Stender Steen, Køber Lars, Torp-Pedersen Christian, Poulsen Henrik E
Abstract excerpt
AIM: Pharmacogenetics can be used as a tool for stratified pharmacological therapy in cardiovascular medicine. We investigated whether a predefined combination of the Arg389Gly polymorphism in the adrenergic β(1) -receptor gene (ADRB1) and the Gln27Glu polymorphism in the adrenergic β(2) -recepto...
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