Article
Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse.
Genetics - 1 Jul 2011
Stottmann R W, Moran J L, Turbe-Doan A, Driver E, Kelley M, Beier D R
Abstract excerpt
The control of growth, patterning, and differentiation of the mammalian forebrain has a large genetic component, and many human disease loci associated with cortical malformations have been identified. To further understand the genes involved in controlling neural development, we have performed a forward genetic screen in the mouse (Mus musculus) using ENU mutagenesis. We report the results from our ENU screen in...
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