Article
Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.
Developmental biology - 15 Jul 2016
Palmer Kristina, Fairfield Heather, Borgeia Suhaib, Curtain Michelle, Hassan Mohamed G, Dionne Louise, Yong Karst Son, Coombs Harold, Bronson Roderick T, Reinholdt Laura G, Bergstrom David E, Donahue Leah Rae, Cox Timothy C, Murray Stephen A
Abstract excerpt
Craniofacial abnormalities are among the most common features of human genetic syndromes and disorders. The etiology of these conditions is often complex, influenced by both genetic context and the environment. Frequently, craniofacial abnormalities present as part of a syndrome with clear comorbid phenotypes, providing additional insight into mechanisms of the causative gene or pathway. The mouse has been a key...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.