Article
Rip2 participates in Bcl10 signaling and T-cell receptor-mediated NF-kappaB activation.
The Journal of biological chemistry - 9 Jan 2004
Ruefli-Brasse Astrid A, Lee Wyne P, Hurst Stephen, Dixit Vishva M
Abstract excerpt
Engagement of the T-cell receptor (TCR) initiates a signaling cascade that ultimately results in activation of the transcription factor NF-kappaB, which regulates many T-cell functions including proliferation, differentiation and cytokine production. Herein we demonstrate that Rip2, a caspase rec...
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