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Article

Specific p53 mutations predict poor prognosis in oral squamous cell carcinoma.

Oral oncology - 1 Feb 2003

Yamazaki Yutaka, Chiba Itsuo, Hirai Atsuko, Sugiura Chihiro, Notani Ken-ichi, Kashiwazaki Haruhiko, Tei Kanchu, Totsuka Yasunori, Fukuda Hiroshi

Abstract excerpt

In this study, we focused on p53 mutations in specific regions, including DNA-binding surface regions, to clarify the correlation between mutations within the specific regions of p53 and clinical outcomes of patients with oral cancers. We analyzed p53 mutations in 121 fresh primary oral squamous cell carcinomas (SCCs) by polymerase chain reaction-single-strand conformation polymorphism or a yeast functional...

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Share to Carcinoma, Squamous Cell
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 12509970
DOI: 10.1016/s1368-8375(02)00064-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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