Article
Interleukin-4 induces expression of the CD45RA antigen on human thymocyte subpopulations.
International immunology - 1 Jan 1990
Uittenbogaart C H, Higashitani S, Schmid I, Vollger L W, Boone T, Clement L T
Abstract excerpt
Interleukin-4 (IL-4) is a multifunctional lymphokine which promotes the growth and/or maturation of multiple cell types. We have examined the ability of IL-4 to promote the phenotypic maturation of subsets of human thymocytes. When cultured in serum-free medium supplemented with recombinant IL-4, a subset of immature CD3-CD45RA- human thymocytes ceased to express the CD1 common thymocyte antigen and acquired...
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