Article
Phenotype transition of CD4+ T cells from CD45RA to CD45R0 is accompanied by cell activation and proliferation.
Cytometry - 1 Apr 1995
Johannisson A, Festin R
Abstract excerpt
An investigation of proliferation and activation events in subsets of human CD4+ cells, defined by their expression of CD45RA and CD45R0, is reported. A single-laser based assay for the study of multiple surface antigens and two-parameter cell cycle analysis was used for sorting of and subsequent analysis of proliferation in CD4+CD45RA+ CD45R0-, CD4+CD45RA-CD45R0+ subsets and phenotypically intermediate stages....
Topics
- CD4-Positive T-Lymphocytes
- Cell Division
- Cell Separation
- DNA
- Flow Cytometry
- Humans
- In Vitro Techniques
- Leukocyte Common Antigens
- Light
- Lymphocyte Activation
- Phenotype
- Scattering, Radiation