Article
Phenotypical and functional differentiation of CD4+ CD45RA+ human T cells following polyclonal activation.
Scandinavian journal of immunology - 1 Sept 1990
Kristensson K, Dohlsten M, Fischer H, Ericsson P O, Hedlund G, Sjögren H O, Carlsson R
Abstract excerpt
Human CD4+ T cells differ in their expression of the leucocyte common antigen. Antibodies detecting certain forms (CD45RA and CD45RO) of this antigen have been used to identify and isolate subpopulations of the CD4+ T cells. These isolated subsets have been shown to have different abilities concerning lymphokine production and provision of help to B cells for Ig production. When these T-cell subsets were...
Topics
- Antigens, Differentiation
- CD4 Antigens
- Cell Differentiation
- Cell Division
- Humans
- Leukocyte Common Antigens
- Lymphocyte Activation
- Phenotype
- T-Lymphocytes