CD4+CD45RA+ and CD4+CD45RA- T cell subsets in man maintain distinct function and CD45RA expression persists on a subpopulation of CD45RA+ cells after activation with Con A.

doi:10.1016/0008-8749(90)90220-l

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Article

CD4+CD45RA+ and CD4+CD45RA- T cell subsets in man maintain distinct function and CD45RA expression persists on a subpopulation of CD45RA+ cells after activation with Con A.

Cellular immunology - 1 Sept 1990

Rothstein D M, Sohen S, Daley J F, Schlossman S F, Morimoto C

Abstract excerpt

We have previously shown that Con A-induced suppressor T cells belong to the CD45RA+ subset. After unseparated T cells are activated with Con A, CD45RA expression increases to a maximum (Day 2), and then decreases significantly, but does not disappear entirely (Day 9), while CD29 expression incre...

Topics

Antigens, CD
Antigens, Differentiation
CD4-Positive T-Lymphocytes
Concanavalin A
Humans
Immunoglobulin G
In Vitro Techniques
Integrin beta1
Leukocyte Common Antigens
Lymphocyte Activation
Molecular Weight
Phenotype
Pokeweed Mitogens
Precipitin Tests
T-Lymphocytes, Helper-Inducer
T-Lymphocytes, Regulatory

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Open in PubMed

Identifiers

PMID: 1696528
DOI: 10.1016/0008-8749(90)90220-l

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1696528-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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