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Article

DNA methylation predicts recurrence from resected stage III proximal colon cancer.

Cancer - 1 May 2011

Ahn Joong Bae, Chung Woon Bok, Maeda Osamu, Shin Sang Joon, Kim Hyun Soo, Chung Hyun Chul, Kim Nam Kyu, Issa Jean-Pierre J

Abstract excerpt

BACKGROUND: In colorectal cancer (CRC), DNA methylation anomalies define distinct subgroups termed CpG island methylator phenotype 1 (CIMP1), CIMP2, and CIMP-negative. The role of this classification in predicting recurrence and disease-free survival (DFS) in resected stage III CRC was evaluated. METHODS: Sporadic cancers from 161 patients were analyzed. Bisulfite pyrosequencing was used to examine the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21509761
DOI: 10.1002/cncr.25737
PMCID: PMC3117123

Genes

BRAF
KRAS
SFRP1
SFRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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