Article
Homodimerization of the Src homology 3 domain of the calcium channel β-subunit drives dynamin-dependent endocytosis.
The Journal of biological chemistry - 24 Jun 2011
Miranda-Laferte Erick, Gonzalez-Gutierrez Giovanni, Schmidt Silke, Zeug Andre, Ponimaskin Evgeni G, Neely Alan, Hidalgo Patricia
Abstract excerpt
Voltage-dependent calcium channels constitute the main entry pathway for calcium into excitable cells. They are heteromultimers formed by an α(1) pore-forming subunit (Ca(V)α(1)) and accessory subunits. To achieve a precise coordination of calcium signals, the expression and activity of these channels is tightly controlled. The accessory β-subunit (Ca(V)β), a membrane associated guanylate kinase containing one...
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