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Article

Several structural domains contribute to the regulation of N-type calcium channel inactivation by the beta 3 subunit.

The Journal of biological chemistry - 30 Jan 2004

Stotz Stephanie C, Barr Wendy, McRory John E, Chen Lina, Jarvis Scott E, Zamponi Gerald W

Abstract excerpt

Calcium channel beta subunits are essential regulatory elements of the gating properties of high voltage-activated calcium channels. Co-expression with beta(3) subunits typically accelerates inactivation, whereas co-expression with beta(4) subunits results in a slowly inactivating phenotype. Here, we have examined the molecular basis of the differential effect of these two subunits on the inactivation...

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Source

Identifiers

PMID: 14602720
DOI: 10.1074/jbc.M308991200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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