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Article

Calcium channel function regulated by the SH3-GK module in beta subunits.

Neuron - 8 Apr 2004

McGee Aaron W, Nunziato Deborah A, Maltez Janet M, Prehoda Kenneth E, Pitt Geoffrey S, Bredt David S

Abstract excerpt

beta subunits of voltage-gated calcium channels (VGCCs) regulate channel trafficking and function, thereby shaping the intensity and duration of intracellular changes in calcium. beta subunits share limited sequence homology with the Src homology 3-guanylate kinase (SH3-GK) module of membrane-associated guanylate kinases (MAGUKs). Here, we show biochemical similarities between beta subunits and MAGUKs, revealing...

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PMID: 15066267
DOI: 10.1016/s0896-6273(04)00149-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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