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Article

New strategies in Barrett's esophagus: integrating clonal evolutionary theory with clinical management.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2011

Reid Brian J, Kostadinov Rumen, Maley Carlo C

Abstract excerpt

Barrett's esophagus is a condition in which the normal stratified squamous epithelium of the distal esophagus is replaced by intestinal metaplasia. For more than three decades, the prevailing clinical paradigm has been that Barrett's esophagus is a complication of symptomatic reflux disease that predisposes to esophageal adenocarcinoma. However, no clinical strategy for cancer prevention or early detection based...

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Source

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Identifiers

PMID: 21498395
DOI: 10.1158/1078-0432.CCR-09-2358
PMCID: PMC3119197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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