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Esophageal Cancer: Genomic and Molecular Characterization, Stem Cell Compartment and Clonal Evolution

14 Sept 2017

Abstract excerpt

Esophageal cancer (EC) is the eighth most common cancer and is the sixth leading cause of death worldwide. The incidence of histologic subtypes of EC, esophageal adenocarcinoma (EAC) and esophageal squamous carcinoma (ESCC), display considerable geographic variation. EAC arises from metaplastic Barrett's esophagus (BE) in the context of chronic inflammation secondary to exposure to acid and bile. The main risk...

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PMID: 28930282
DOI: 10.3390/medicines4030067

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