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Consumption of probiotics increases the effect of regulatory T cells in transfer colitis

14 Apr 2011

Abstract excerpt

BACKGROUND: Probiotics may alter immune regulation. Recently, we showed that the probiotic bacteria Lactobacillus acidophilus NCFM™ influenced the activity of regulatory T cells (Tregs) in vitro. The aim of the present work was to demonstrate if L. acidophilus NCFM™ also affects the function of Tregs in vivo. METHODS: Development of colitis after transfer of CD4+CD25- T cells and protection from colitis by Tregs...

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PMID: 21495121
DOI: 10.1002/ibd.21709

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