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Article

Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes.

Gastroenterology - 1 Mar 2011

Parekkadan Biju, Upadhyay Rabi, Dunham Joshua, Iwamoto Yoshiko, Mizoguchi Emiko, Mizoguchi Atsushi, Weissleder Ralph, Yarmush Martin L

Abstract excerpt

BACKGROUND & AIMS: Bone marrow stromal cells (MSCs) are being evaluated as a cellular therapeutic for immune-mediated diseases. We investigated the effects of MSCs in mice with chemically induced colitis and determined the effects of CD11b(+) cells based on the hypothesis that MSCs increase numbers of regulatory T cells. METHODS: Colitis was induced in mice using trinitrobenzene sulfonic acid; symptoms were...

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Identifiers

PMID: 20955701
DOI: 10.1053/j.gastro.2010.10.013
PMCID: PMC3033974

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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