Article
Negative impact of bone-marrow-derived mesenchymal stem cells on dextran sulfate sodium-induced colitis.
World journal of gastroenterology - 21 Feb 2015
Nam Young-Sun, Kim Nayoun, Im Keon-Il, Lim Jung-Yeon, Lee Eun-Sol, Cho Seok-Goo
Abstract excerpt
AIM: To investigate the effects of mesenchymal stem cells (MSCs) on dextran sulfate sodium-induced inflammatory bowel disease (IBD). METHODS: C57BL/6 mice were fed 3.5% (g/L) dextran sulfate sodium. On day seven, the mice received intraperitoneal injections of 1×10(6) MSCs. The survival rate, disease activity index values, and body weight, were monitored daily. On day ten, colon lengths and histopathologic...
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