Article
Estimating genome-wide IBD sharing from SNP data via an efficient hidden Markov model of LD with application to gene mapping.
Bioinformatics (Oxford, England) - 15 Jun 2010
Bercovici Sivan, Meek Christopher, Wexler Ydo, Geiger Dan
Abstract excerpt
MOTIVATION: Association analysis is the method of choice for studying complex multifactorial diseases. The premise of this method is that affected persons contain some common genomic regions with similar SNP alleles and such areas will be found in this analysis. An important disadvantage of GWA s...
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