Article

Fast and accurate shared segment detection and relatedness estimation in un-phased genetic data using TRUFFLE

2018-11-04

Abstract excerpt

Relationship estimation and segment detection between individuals is an important aspect of disease gene mapping. Existing methods are either tailored for computational efficiency, or require phasing to improve accuracy. We developed TRUFFLE, a method that integrates computational techniques and statistical principles for the identification and visualization of identity-by-descent (IBD) segments using un-phased da...

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Literature Corpus work: b4d5463e-2978-51e7-b00e-893f2a095d13
DOI: 10.1101/460915

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