Article
Joint inference of identity by descent along multiple chromosomes from population samples.
Journal of computational biology : a journal of computational molecular cell biology - 1 Mar 2014
Zheng Chaozhi, Kuhner Mary K, Thompson Elizabeth A
Abstract excerpt
There has been much interest in detecting genomic identity by descent (IBD) segments from modern dense genetic marker data and in using them to identify human disease susceptibility loci. Here we present a novel Bayesian framework using Markov chain Monte Carlo (MCMC) realizations to jointly infer IBD states among multiple individuals not known to be related, together with the allelic typing error rate and the...
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