Article
Recipes and mechanisms of cellular reprogramming: a case study on budding yeast Saccharomyces cerevisiae.
BMC systems biology - 12 Apr 2011
Ding Shengchao, Wang Wei
Abstract excerpt
BACKGROUND: Generation of induced pluripotent stem cells (iPSCs) and converting one cell type to another (transdifferentiation) by manipulating the expression of a small number of genes highlight the progress of cellular reprogramming, which holds great promise for regenerative medicine. A key challenge is to find the recipes of perturbing genes to achieve successful reprogramming such that the reprogrammed cells...
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