Article
A living vector field reveals constraints on galactose network induction in yeast.
Molecular systems biology - 30 Jan 2017
Stockwell Sarah R, Rifkin Scott A
Abstract excerpt
When a cell encounters a new environment, its transcriptional response can be constrained by its history. For example, yeast cells in galactose induce GAL genes with a speed and unanimity that depends on previous nutrient conditions. Cellular memory of long-term glucose exposure delays GAL induction and makes it highly variable with in a cell population, while other nutrient histories lead to rapid, uniform...
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