Article

Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity

2020-06-12

Abstract excerpt

Our ability to identify the particular transcription factors that maintain cell type is limited. Identification of factors by their cell type-specific expression or their participation in developmental regulation has been only modestly successful. We hypothesized that because cell type is often resilient to perturbations, the transcriptional response to perturbations would identify identity-maintaining factors. We...

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Literature Corpus work: d8b3646b-6fd9-56a7-ac5e-16c1ef8e0bcb
DOI: 10.1101/2020.06.11.147207

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