Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systematic search for recipes to generate induced pluripotent stem cells.

PLoS computational biology - 1 Dec 2011

Chang Rui, Shoemaker Robert, Wang Wei

Abstract excerpt

Generation of induced pluripotent stem cells (iPSCs) opens a new avenue in regenerative medicine. One of the major hurdles for therapeutic applications is to improve the efficiency of generating iPSCs and also to avoid the tumorigenicity, which requires searching for new reprogramming recipes. We present a systems biology approach to efficiently evaluate a large number of possible recipes and find those that are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Embryonic Stem Cells
Share to Induced Pluripotent Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Regenerative Medicine

Share to Systems Biology

Source

Open in PubMed Open full text

Identifiers

PMID: 22215993
DOI: 10.1371/journal.pcbi.1002300
PMCID: PMC3245295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systematic search for recipes to generate induced pluripotent stem cells.PMID 22215993Read ↗

Recipes and mechanisms of cellular reprogramming: a case study on budding yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

A Perturbation Cell Atlas of Human Induced Pluripotent Stem CellsSemantic proximity Read ↗

A fast 2C-induction method reveals a barrier role of SP2 for totipotencySemantic proximity Read ↗

Concise Review: The Magic Act of Generating Induced Pluripotent Stem Cells: Many Rabbits in the HatSemantic proximity Read ↗

Protocol for highly efficient and rapid generation of human pluripotent stem cells (hCiPSCs) by chemical reprogrammingSemantic proximity Read ↗

Induction and maintenance of mouse totipotent stem cells by a defined chemical cocktailSemantic proximity Read ↗

A molecular roadmap for induced multi-lineage trans-differentiation of fibroblasts by chemical combinations.Semantic proximity Read ↗

Phenotypic technologies in stem cell biology.Semantic proximity Read ↗

Reprogramming cell fates by small moleculesSemantic proximity Read ↗

A chemical genetics approach for specific differentiation of stem cells to somatic cells: a new promising therapeutical approach.Semantic proximity Read ↗

Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical InhibitorsSemantic proximity Read ↗

Cell reprogramming: a new chemical approach to stem cell biology and tissue regeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.