Article

scREMOTE: Using multimodal single cell data to predict regulatory gene relationships and to build a computational cell reprogramming model

2021-10-12

Abstract excerpt

Cell reprogramming offers a potential treatment to many diseases, by regenerating specialized somatic cells. Despite decades of research, discovering the transcription factors that promote cell reprogramming has largely been accomplished through trial and error, a time-consuming and costly method. A computational model for cell reprogramming, however, could guide the hypothesis formulation and experimental validat...

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Literature Corpus work: 9cc1c77b-e187-53af-b318-dc91246d44e7
DOI: 10.1101/2021.10.11.463798

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