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Article

Association of polymorphisms and haplotypes of the NBN gene with laryngeal cancer and multiple primary tumors of the head and neck.

Head & neck - 1 Mar 2012

Ziółkowska-Suchanek Iwona, Mosor Maria, Wierzbicka Małgorzata, Fichna Marta, Rydzanicz Małgorzata, Nowak Jerzy

Abstract excerpt

BACKGROUND: We investigated whether genetic polymorphisms of the DNA repair gene NBN are associated with head and neck cancer risk. METHODS: We analyzed 6 polymorphisms in 175 patients with a single laryngeal tumor, 104 with multiple primary tumors but 1 malignancy (primary/second) localized in the larynx, 60 patients with multiple primary tumors localized in the head or neck, and 275 controls. RESULTS: Although...

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PMID: 21472885
DOI: 10.1002/hed.21741

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NBN

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