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Article

Haplotype analysis of XRCC2 gene polymorphisms and association with increased risk of head and neck cancer.

Scientific reports - 16 Oct 2017

Saeed Soma, Mahjabeen Ishrat, Sarwar Romana, Bashir Kashif, Kayani Mahmood Akhtar

Abstract excerpt

We aimed to investigate the effect of hotspot variations of XRCC2 gene on the risk of head and neck cancer (HNC) in 400 patients and 400 controls. Five polymorphisms of XRCC2 gene G4234C (rs3218384), G4088T (rs3218373), G3063A (rs2040639), R188H (rs3218536) and rs7802034 were analyzed using Allele- specific polymerase chain reaction (ARMS-PCR) followed by sequence analysis. For , the GG genotype...

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Source

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Identifiers

PMID: 29038438
DOI: 10.1038/s41598-017-13461-6
PMCID: PMC5643489

Genes

XRCC2

Variants

rs3218384
rs3218384
rs3218384
rs3218384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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