Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Variation in the 3'-Untranslated Region of NBN Gene Is Associated with Gastric Cancer Risk in a Chinese Population.

PloS one - 1 Jan 2015

Sun Ping, Du Jiangbo, Zhu Xun, Ren Chuanli, Xie Lan, Dai Ningbin, Gu Yayun, Yan Caiwang, Dai Juncheng, Ma Hongxia, Jiang Yue, Chen Jiaping, Hu Zhibin, Shen Hongbing, Wu Haorong, Jin Guangfu

Abstract excerpt

NBN plays a crucial role in carcinogenesis as a core component for both homologous recombination (HR) and non-homologous end-joining (NHEJ) DNA double-strand breaks (DSBs) repair pathways. Genetic variants in the NBN gene have been associated with multiple cancers risk, suggesting pleiotropic effect on cancer. We hypothesized that genetic variants in the NBN gene may modify the risk of gastric cancer. To test...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Cell Cycle Proteins

Share to Genetic Association Studies

Share to Haplotypes

Share to Nuclear Proteins

Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 26402912
DOI: 10.1371/journal.pone.0139059
PMCID: PMC4581712

Genes

NBN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Variation in the 3'-Untranslated Region of NBN Gene Is Associated with Gastric Cancer Risk in a Chinese Population.PMID 26402912Read ↗

Genetic variants in the nucleotide excision repair pathway genes and gastric cancer susceptibility in a southern Chinese populationSemantic proximity Read ↗

Associations between NBS1 Polymorphisms and Colorectal Cancer in Chinese Population.Semantic proximity Read ↗

Potentially functional variants in the core nucleotide excision repair genes predict survival in Japanese gastric cancer patients.Semantic proximity Read ↗

Genetic variation of CTNNB1 gene is associated with susceptibility and prognosis of gastric cancer in a Chinese population.Semantic proximity Read ↗

NBS1 rs2735383 polymorphism is associated with an increased risk of laryngeal carcinoma.Semantic proximity Read ↗

Functional long non-coding RNAs associated with gastric cancer susceptibility and evaluation of the epidemiological efficacy in a central Chinese population.Semantic proximity Read ↗

Polymorphisms of multiple genes involved in NER pathway predict prognosis of gastric cancer.Semantic proximity Read ↗

Nucleotide excision repair related gene polymorphisms and genetic susceptibility, chemotherapeutic sensitivity and prognosis of gastric cancer.Semantic proximity Read ↗

Association of nucleotide excision repair pathway gene polymorphisms with gastric cancer and atrophic gastritis risks.Semantic proximity Read ↗

A functional polymorphism at microRNA-629-binding site in the 3'-untranslated region of NBS1 gene confers an increased risk of lung cancer in Southern and Eastern Chinese population.Semantic proximity Read ↗

YTHDC1 gene polymorphisms and neuroblastoma susceptibility in Chinese children.Semantic proximity Read ↗

Effect of ERCC8 tagSNPs and their association with H. pylori infection, smoking, and alcohol consumption on gastric cancer and atrophic gastritis risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.