Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms and haplotypes of the NBS1 gene in childhood acute leukaemia.

European journal of cancer (Oxford, England : 1990) - 1 Oct 2008

Mosor Maria, Ziółkowska Iwona, Januszkiewicz-Lewandowska Danuta, Nowak Jerzy

Abstract excerpt

DNA repair gene polymorphisms and mutations may influence cancer risk. The product of the NBS1 gene, nibrin, is functionally involved in the double-strand DNA break repair system. Heterozygous, germline mutations of the NBS1 gene are associated with an increased risk of tumours. Thus, common polymorphism and haplotypes of NBS1 may contribute to the risk of cancer. This study verified whether polymorphisms of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Leukemia
Share to Acute Disease
Share to Cell Cycle Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Haplotypes

Share to Infant

Share to Neoplasm Proteins

Share to Nuclear Proteins

Source

Identifiers

PMID: 18691878
DOI: 10.1016/j.ejca.2008.06.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms and haplotypes of the NBS1 gene in childhood acute leukaemia.PMID 18691878Read ↗

NBN and XRCC3 genetic variants in childhood acute lymphoblastic leukaemia.Semantic proximity Read ↗

657del5 mutation in the gene for Nijmegen breakage syndrome (NBS1) in a cohort of Russian children with lymphoid tissue malignancies and controls.Semantic proximity Read ↗

Functional polymorphisms in the NBS1 gene and acute lymphoblastic leukemia susceptibility in a Chinese population.Semantic proximity Read ↗

New mutations and protein variants of NBS1 are identified in cancer cell lines.Semantic proximity Read ↗

NBS1 rs1805794G>C polymorphism is associated with decreased risk of acute myeloid leukemia in a Chinese population.Semantic proximity Read ↗

Association of the heterozygous germline I171V mutation of the NBS1 gene with childhood acute lymphoblastic leukemiaSemantic proximity Read ↗

Germline Genetic NBN Variation and Predisposition to B-cell Acute Lymphoblastic Leukemia in ChildrenSemantic proximity Read ↗

Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia.Semantic proximity Read ↗

Heterozygous carriers of the I171V mutation of the NBS1 gene have a significantly increased risk of solid malignant tumours.Semantic proximity Read ↗

Functional variants in NBS1 and cancer risk: evidence from a meta-analysis of 60 publications with 111 individual studies.Semantic proximity Read ↗

Associations between NBS1 Polymorphisms and Colorectal Cancer in Chinese Population.Semantic proximity Read ↗

Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.