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Genetic Polymorphisms and Head and Neck Cancer Outcomes: A Review

1 Mar 2008

Abstract excerpt

Head and neck cancer (HNC) patients have variable prognoses even within the same clinical stage and while receiving similar treatments. The number of studies of genetic polymorphisms as prognostic factors of HNC outcomes is growing. Candidate polymorphisms have been evaluated in DNA repair, cell cycle, xenobiotic metabolism, and growth factor pathways. Polymorphisms of XRCC1, FGFR, and CCND1 have been...

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PMID: 18349267
DOI: 10.1158/1055-9965.epi-07-2714

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