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Article

Hypermethylation, risk factors, clinical characteristics, and survival in 235 patients with laryngeal and hypopharyngeal cancers

4 Sept 2007

Abstract excerpt

BACKGROUND: It has been established that promoter hypermethylation occurs in several genes during the pathogenesis of head and neck cancer. The authors investigated the role played by the hypermethylation of 4 cancer-related genes in the survival of patients who had laryngeal and hypopharyngeal cancer and in the occurrence of second primary tumors. METHODS: Archival paraffin-embedded tissue (PET) samples were...

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Share to Epigenetics and DNA Methylation
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PMID: 17786935
DOI: 10.1002/cncr.22975

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