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Neuron-Specific DNA Methylation Differences in the Prefrontal Cortex in Parkinson’s Disease

2026-02-09

Abstract excerpt

Parkinson’s disease (PD) is a progressive movement disorder that affects over ten million individuals worldwide. While the involvement of genetically-driven cellular mechanisms in PD pathogenesis is well-established, there is increasing evidence that epigenetic dysregulation also plays a key role. We profiled genome-wide DNA methylation in isolated neuronal, oligodendrocyte and other glial nuclei populations from...

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Literature Corpus work
f76c625a-b956-537f-bbb2-cdb91e8bc796
DOI
10.64898/2026.02.03.26344617
Open publication

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