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Article

MDR-1 gene polymorphisms in steroid-responsive versus steroid-resistant nephrotic syndrome in children.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Dec 2011

Jafar Tabrez, Prasad Narayan, Agarwal Vikas, Mahdi Abbas, Gupta Amit, Sharma Raj K, Negi Mahendra Pal Singh, Agrawal Suraksha

Abstract excerpt

BACKGROUND: The putative genetic regulation of multidrug resistance gene-1 (MDR-1) gene expression and P-glycoprotein function has not yet been clearly delineated in patients with nephrotic syndrome (NS). We undertook this study to examine the distribution of three most frequent MDR-1 exonic polymorphisms G3435C, G2677T/A and C1236T in patients with NS and control children to investigate their usefulness as...

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Source

Identifiers

PMID: 21460357
DOI: 10.1093/ndt/gfr150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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