A PRISMA-compliant meta-analysis of MDR1 polymorphisms and idiopathic nephrotic syndrome: Susceptibility and steroid responsiveness.

doi:10.1097/MD.0000000000007191

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A PRISMA-compliant meta-analysis of MDR1 polymorphisms and idiopathic nephrotic syndrome: Susceptibility and steroid responsiveness.

Medicine - 1 Jun 2017

Han Shi-Sheng, Xu Yan-Qiu, Lu Yan, Gu Xiang-Chen, Wang Yi

Abstract excerpt

BACKGROUND: Studies have investigated rs1128503, rs1045642, and rs2032582 in multidrug resistance protein 1 (MDR1) for association with susceptibility to idiopathic nephrotic syndrome (INS) and steroid resistance. However, because these findings were inconsistent, we performed a meta-analysis to determine whether there was evidence of a role of these MDR1 variants in INS. METHODS: The PubMed, Embase, and Web of...

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ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Drug Resistance

INS gene

Genetic Predisposition to Disease

Nephrotic Syndrome

Polymorphism, Single Nucleotide

Steroids

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PMID: 28614261
DOI: 10.1097/MD.0000000000007191
PMCID: PMC5478346

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