Article
Association of ACE and MDR1 Gene Polymorphisms with Steroid Resistance in Children with Idiopathic Nephrotic Syndrome.
Genetic testing and molecular biomarkers - 1 Aug 2015
Dhandapani Mohanapriya Chinambedu, Venkatesan Vettriselvi, Rengaswamy Nammalwar Bollam, Gowrishankar Kalpana, Nageswaran Prahlad, Perumal Venkatachalam
Abstract excerpt
AIM: The purpose of the study was to investigate the distribution of insertion/deletion (I/D) polymorphisms of the angiotensin-converting enzyme (ACE) gene and three exonic polymorphisms of the multidrug resistance 1 (MDR1) gene (C3435T, C1236T, and G2677T) in children diagnosed with idiopathic nephrotic syndrome (INS). MATERIALS AND METHODS: The study group consisted of 100 healthy controls and 150 INS patients,...
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