Article
Polymorphisms of the MDR1 and MIF genes in children with nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) - 1 Nov 2011
Choi Hyun Jin, Cho Hee Yeon, Ro Han, Lee So Hee, Han Kyung Hee, Lee Hyunkyung, Kang Hee Gyung, Ha Il Soo, Choi Yong, Cheong Hae Il
Abstract excerpt
Oral steroid treatment is the first line of therapy for childhood nephrotic syndrome (NS). Nonetheless, some patients are resistant to this treatment. Many efforts have been made to explain the differences in the response to steroid treatment in patients with NS based on the genetic background. We have investigated single nucleotide polymorphisms of the MDR1 [C1236T (rs1128503), G2677T/A (rs2032582), and C3435T...
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