Article
MDR-1 gene polymorphisms and clinical course of steroid-responsive nephrotic syndrome in children.
Pediatric nephrology (Berlin, Germany) - 1 Jan 2007
Wasilewska Anna, Zalewski Grzegorz, Chyczewski Lech, Zoch-Zwierz Walentyna
Abstract excerpt
The study was aimed at investigating the association between MDR-1 genetic polymorphisms [C1236T, G2677T(A), C3435T] and parameters describing the clinical course and treatment response of childhood steroid-responsive nephrotic syndrome (SRNS). Three MDR-1 genetic markers were analyzed in 108 children diagnosed with SRNS and in 135 healthy controls with neither allergic nor renal disease. All subjects were...
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