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Article

Multi-drug resistance-1 gene polymorphisms in nephrotic syndrome: impact on susceptibility and response to steroids.

Gene - 10 Nov 2013

Youssef Doaa M, Attia Tarek A, El-Shal Amal S, Abduelometty Fawzya A

Abstract excerpt

BACKGROUND: Role of multidrug resistance-1 (MDR-1) gene polymorphisms has not been clarified in nephrotic syndrome (NS). Additionally, researchers studied several genetic polymorphisms to explain their influence on different patients' responses to steroid; however the data were inconsistent. Therefore, we aimed to investigate the association of MDR-1 gene polymorphisms [C1236T, G2677T/A, C3435T] and haplotypes...

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Identifiers

PMID: 23994685
DOI: 10.1016/j.gene.2013.08.045

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