Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tobacco-smoking-related differential DNA methylation: 27K discovery and replication.

American journal of human genetics - 8 Apr 2011

Breitling Lutz P, Yang Rongxi, Korn Bernhard, Burwinkel Barbara, Brenner Hermann

Abstract excerpt

Tobacco smoking is responsible for substantial morbidity and mortality worldwide, in particular through cardiovascular, pulmonary, and malignant pathology. CpG methylation might plausibly play a role in a variety of smoking-related phenomena, as suggested by candidate gene promoter or global methylation studies. Arrays allowing hypothesis-free searches on a scale resembling genome-wide studies of SNPs have become...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to DNA Methylation
Share to DNA Primers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oligonucleotide Array Sequence Analysis

Share to Receptors, Thrombin

Share to Reproducibility of Results

Share to Smoking

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Open in PubMed Open full text

Identifiers

PMID: 21457905
DOI: 10.1016/j.ajhg.2011.03.003
PMCID: PMC3071918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tobacco-smoking-related differential DNA methylation: 27K discovery and replication.PMID 21457905Read ↗

Epigenetic Signatures of Cigarette Smoking.Semantic proximity Read ↗

The impact of genetic variation and cigarette smoke on DNA methylation in current and former smokers from the COPDGene study.Semantic proximity Read ↗

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk.Semantic proximity Read ↗

Current genetics and epigenetics of smoking/tobacco-related cardiovascular disease.Semantic proximity Read ↗

Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation.Semantic proximity Read ↗

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts.Semantic proximity Read ↗

Smoking and atherosclerotic cardiovascular disease: part IV: genetic markers associated with smoking.Semantic proximity Read ↗

A Whole-Blood Transcriptome Meta-Analysis Identifies Gene Expression Signatures of Cigarette SmokingSemantic proximity Read ↗

Smoking-related changes in DNA methylation and gene expression are associated with cardio-metabolic traits.Semantic proximity Read ↗

DNA methylation assay based on pyrosequencing for determination of smoking statusSemantic proximity Read ↗

From tobacco smoking to mutational signature: the role of epigenetic changes in human cancersSemantic proximity Read ↗

Novel region discovery method for Infinium 450K DNA methylation data reveals changes associated with aging in muscle and neuronal pathways.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.