Article
Smoking and atherosclerotic cardiovascular disease: part IV: genetic markers associated with smoking.
Biomarkers in medicine - 1 Apr 2010
Winkelmann Bernhard R, von Holt Klaus, Unverdorben Martin
Abstract excerpt
Genes influence smoking behavior, affect the metabolism of nicotine and specific chemicals produced during combustion, and enhance (or diminish) pathomechanistic pathways associated with the atherogenic potential of smoking, including oxidative stress, its inflammatory burden or procoagulant potential. Genome-wide association studies have revolutionized the search for new functional genetic markers with ever...
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