Article

From tobacco smoking to mutational signature: the role of epigenetic changes in human cancers

2020-01-17

Abstract excerpt

<title>Abstract</title> <p>Background Tobacco smoking is associated with a unique mutational signature in the human cancer genome. It is unclear whether tobacco smoking -altered DNA methylations and gene expressions affect smoking-related mutational signature.Methods We evaluated the smoking-related DNA methylation sites reported from five previous studies using peripheral blood cells to identify possible target...

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Literature Corpus work: 6b5657da-b7e7-5a43-a7df-b788cb310f62
DOI: 10.21203/rs.2.21105/v1

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