DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk.

doi:10.1002/ijc.30431

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk.

International journal of cancer - 1 Jan 2017

Baglietto Laura, Ponzi Erica, Haycock Philip, Hodge Allison, Bianca Assumma Manuela, Jung Chol-Hee, Chung Jessica, Fasanelli Francesca, Guida Florence, Campanella Gianluca, Chadeau-Hyam Marc, Grankvist Kjell, Johansson Mikael, Ala Ugo, Provero Paolo, Wong Ee Ming, Joo Jihoon, English Dallas R, Kazmi Nabila, Lund Eiliv, Faltus Christian, Kaaks Rudolf, Risch Angela, Barrdahl Myrto, Sandanger Torkjel M, Southey Melissa C, Giles Graham G, Johansson Mattias, Vineis Paolo, Polidoro Silvia, Relton Caroline L, Severi Gianluca

Abstract excerpt

DNA methylation changes are associated with cigarette smoking. We used the Illumina Infinium HumanMethylation450 array to determine whether methylation in DNA from pre-diagnostic, peripheral blood samples is associated with lung cancer risk. We used a case-control study nested within the EPIC-Italy cohort and a study within the MCCS cohort as discovery sets (a total of 552 case-control pairs). We validated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA

Share to DNA Methylation

Share to Early Detection of Cancer

Share to Epigenesis, Genetic

Share to Lung Neoplasms

Share to Microarray Analysis

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 27632354
DOI: 10.1002/ijc.30431
PMCID: PMC5731426

Genes

AHRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk.PMID 27632354Read ↗

Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral bloodSemantic proximity Read ↗

Smoking-associated DNA methylation markers predict lung cancer incidence.Semantic proximity Read ↗

Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral bloodSemantic proximity Read ↗

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts.Semantic proximity Read ↗

Genome-wide analysis of DNA methylation in bronchial washingsSemantic proximity Read ↗

Blood cell DNA methylation biomarkers in preclinical malignant pleural mesothelioma: The EPIC prospective cohortSemantic proximity Read ↗

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPDSemantic proximity Read ↗

The impact of genetic variation and cigarette smoke on DNA methylation in current and former smokers from the COPDGene study.Semantic proximity Read ↗

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPDSemantic proximity Read ↗

Identification of novel epigenetic abnormalities as sputum biomarkers for lung cancer risk among smokers and COPD patientsSemantic proximity Read ↗

Epigenetic Signatures of Cigarette Smoking.Semantic proximity Read ↗

Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.